complement component 3


C3 (may also be known as: ASP, Plp, )




LOC100331428 Danio rerio
C3 Homo sapiens
C3 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1527 complement component 3 Molecular liver Mouse C3 5.0% Increase Gene Expression Level

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA487 complement component 3 Molecular skeletal muscle Human C3 16.0% Increase Gene Expression Level
DAA2174 complement component 3 increases with age Molecular hippocampus Human C3 201.6% Increase Gene Expression Level
DAA2186 complement component 3 increases with age Molecular parietal lobe Human C3 108.4% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0001798 positive regulation of type IIa hypersensitivity biological_process
GO:0001970 positive regulation of activation of membrane attack complex biological_process
GO:0006954 inflammatory response biological_process
GO:0006956 complement activation biological_process
GO:0006957 complement activation, alternative pathway biological_process
GO:0006958 complement activation, classical pathway biological_process
GO:0007596 blood coagulation biological_process
GO:0010575 positive regulation vascular endothelial growth factor production biological_process
GO:0010951 negative regulation of endopeptidase activity biological_process
GO:0045087 innate immune response biological_process
GO:0045766 positive regulation of angiogenesis biological_process
GO:0048639 positive regulation of developmental growth biological_process
GO:0050766 positive regulation of phagocytosis biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0004866 endopeptidase inhibitor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0008289 lipid binding molecular_function
GO:0048037 cofactor binding molecular_function