DAA998 |
Changes to elastin fibers in lower dermis |
— |
dermis |
Human |
|
DAA1006 |
Decreased amounts of collagen IV and VII, and abnormal elastin in dermis |
— |
dermis |
Human |
|
DAA995 |
Change in weave of dermis collagen fibers |
— |
dermis |
Human |
|
DAA2588 |
Depletion of hair follicle melanocytes |
— |
hair follicle |
Human |
|
DAA2589 |
Male baldness |
— |
hair |
Human |
|
DAA2587 |
Hair greying |
— |
hair |
Human |
|
DAA2053 |
Sweating capacity decreases |
— |
sweat gland |
Human |
|
DAA999 |
Microvascular alterations in arterioles, capillaries, and venules in dermis/hypodermis |
— |
dermis, subcutaneous |
Human |
|
DAA1001 |
Atrophy of hypodermal layer |
— |
subcutaneous |
Human |
|
DAA742 |
Motor function impairment evident in altered gait and balance |
— |
nervous system |
Human |
|
DAA1983 |
Critical decline in fine motor hand movements |
— |
nervous system |
Human |
|
DAA757 |
Parkinsonian signs |
— |
nervous system |
Human |
|
DAA715 |
Lipid biosynthesis decreases |
— |
central nervous system |
Human |
|
DAA717 |
Dendrite regression, reduction in dendrite length |
— |
brain |
Human |
|
DAA780 |
Medial temporal activation during encoding and retrieval of memory is reduced |
— |
brain |
Human |
|
DAA735 |
Localized increases and decreases in synaptic transmission |
— |
brain |
Human |
|
DAA721 |
Neurofibrillary tangles and Lewy bodies in neurons |
— |
brain |
Human |
|
DAA714 |
Neuronal soma shrinks in size |
— |
brain |
Human |
|
DAA733 |
Neurotransmitter and neuro receptor concentrations are altered |
— |
brain |
Human |
|
DAA784 |
Increased transient activity in non-spatial auditory working memory test |
— |
brain |
Human |
|
DAA783 |
Increased sustained activity in tests of working memory |
— |
brain |
Human |
|
DAA786 |
Increased rhinal cortex activity and functional connectivity in tests for verbal familiarity |
— |
brain |
Human |
|
DAA787 |
Increased bilateral anterior frontal activity in memory interference tests |
— |
brain |
Human |
|
DAA779 |
Prefrontal cortex activation during learning is reduced |
— |
brain |
Human |
|
DAA2595 |
Frequency of somatic mitochondrial mutations increases with age |
— |
brain |
Human |
|