| DAA1962 |
Sirt1 activity decreases |
Sirt1 |
— |
bone marrow |
Mouse |
|
| DAA1969 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) mRNA expression decrease |
Alox5 |
— |
heart |
Mouse |
|
| DAA1964 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) promoter methylation increase |
Alox5 |
— |
cerebellum |
Mouse |
|
| DAA1963 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) promoter methylation increase |
Alox5 |
— |
heart |
Mouse |
|
| DAA1965 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) mRNA expression increase |
Alox5 |
— |
heart |
Mouse |
|
| DAA1970 |
Pdgfra (Platelete derived growth factor receptor a) mRNA levels decline |
Pdgfra |
— |
pancreas |
Mouse |
|
| DAA1972 |
Glutamate-cysteine ligase (GCL) Km decrease |
Gclc |
— |
liver |
Mouse |
|
| DAA1977 |
p16 expression increases |
Cdkn2a |
— |
whole body |
Mouse |
|
| DAA1967 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) mRNA expression increase |
— |
— |
cerebellum |
Mouse |
|
| DAA1966 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) promoter methylation increase |
— |
— |
hippocampus |
Mouse |
|
| DAA1973 |
5-hmC increase in cerebrellum |
— |
— |
cerebellum |
Mouse |
|
| DAA1961 |
Intracellular NAD+ concentration decreases |
— |
— |
bone marrow |
Mouse |
|
| DAA1946 |
vitamin E levels decrease |
— |
— |
blood |
Mouse |
|