DAA1217 |
Brain volume decrease |
Physiological |
brain |
Human |
— |
— |
|
DAA1993 |
Brain volume decreases in a regional-specific way |
Physiological |
brain |
Human |
— |
— |
|
DAA787 |
Increased bilateral anterior frontal activity in memory interference tests |
Physiological |
brain |
Human |
— |
— |
|
DAA765 |
Calcium binding capacity decreases in neurons |
Physiological |
brain |
Human |
— |
— |
|
DAA786 |
Increased rhinal cortex activity and functional connectivity in tests for verbal familiarity |
Physiological |
brain |
Human |
— |
— |
|
DAA737 |
Permeability increases with age |
Physiological |
blood brain barrier |
Human |
— |
— |
|
DAA783 |
Increased sustained activity in tests of working memory |
Physiological |
brain |
Human |
— |
— |
|
DAA784 |
Increased transient activity in non-spatial auditory working memory test |
Physiological |
brain |
Human |
— |
— |
|
DAA1981 |
Selective increase in oxidative damage and decrease in antioxidant function during aging in the substantia nigra |
Physiological |
substantia nigra |
Human |
— |
— |
|
DAA2596 |
Frequency of mitochondrial DNA deletions increases with age |
Physiological |
brain |
Human |
— |
— |
|
DAA762 |
Down regulation of calcium clearance from nerve cells |
Physiological |
brain |
Human |
— |
— |
|
DAA2595 |
Frequency of somatic mitochondrial mutations increases with age |
Physiological |
brain |
Human |
— |
— |
|
DAA1944 |
Ability to acquire motor skills decreases |
Psychological |
brain |
Mouse |
— |
— |
|
DAA1982 |
Learning impairment as assessed by contextual cuing |
Psychological |
brain |
Human |
— |
— |
|
DAA766 |
Speech production problems |
Psychological |
brain |
Human |
— |
— |
|
DAA1939 |
Exploratory behavior is decreased |
Psychological |
brain |
Mouse |
— |
— |
|
DAA754 |
Memory impairment |
Psychological |
brain |
Human |
— |
— |
|
DAA768 |
Increased reliance on vision to control balance |
Psychological |
brain |
Human |
— |
— |
|
DAA1942 |
Balance decreases |
Psychological |
brain |
Mouse |
— |
— |
|
DAA761 |
Activation threshold for long-term potentiation is increased |
Psychological |
brain |
Human |
— |
— |
|
DAA1945 |
Memory consolidation is impaired |
Psychological |
brain |
Mouse |
— |
— |
|
DAA778 |
Variability of performance for multiple cognitive tasks increases |
Psychological |
brain |
Human |
— |
— |
|
DAA776 |
Verbal memory declines |
Psychological |
brain |
Human |
— |
— |
|
DAA748 |
Altered sleep parameters and patterns |
Psychological |
brain |
Human |
— |
— |
|
DAA770 |
Reduction in episodic, working and long-term memory |
Psychological |
brain |
Human |
— |
— |
|