| DAA2386 |
zinc finger protein 549 increases with age |
Molecular |
dermis |
Human |
ZNF549 |
16.0% Increase DNA Methylation |
|
| DAA2385 |
nerve growth factor; beta polypeptide precursor increases with age |
Molecular |
dermis |
Human |
NGF |
19.3% Increase DNA Methylation |
|
| DAA2384 |
cyclin-dependent kinase inhibitor 2B isoform 2 increases with age |
Molecular |
dermis |
Human |
CDKN2B |
26.0% Increase DNA Methylation |
|
| DAA2383 |
sperm associated antigen 7 increases with age |
Molecular |
dermis |
Human |
SPAG7 |
26.1% Increase DNA Methylation |
|
| DAA2051 |
Attenuated vasoconstriction response to cold |
Physiological |
skin |
Human |
— |
— |
|
| DAA2001 |
SIRT1 activity negatively correlated with age in males |
Physiological |
skin |
Human |
SIRT1 |
— |
|
| DAA2000 |
NAD(+) levels decrease with age |
Molecular |
skin |
Human |
— |
— |
|
| DAA1999 |
PARP activity increases with age in males |
Molecular |
skin |
Human |
PARP1 |
— |
|
| DAA1998 |
Lipid oxidation increased with age in males |
Molecular |
skin |
Human |
— |
— |
|
| DAA1997 |
DNA damage increases with age |
Molecular |
skin |
Human |
— |
— |
|
| DAA1202 |
arNOX specific activity increases |
Molecular |
skin |
Human |
ENOX1 |
— |
|
| DAA1011 |
Changes in glycosaminoglycan/proteoglycan |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA1011 |
Changes in glycosaminoglycan/proteoglycan |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA1009 |
Dermal collagen atrophies |
Physiological |
dermis |
Human |
— |
— |
|
| DAA1006 |
Decreased amounts of collagen IV and VII, and abnormal elastin in dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA1005 |
Loss of smooth padding provided by hypodermal fat cells |
Physiological |
skin |
Human |
— |
— |
|
| DAA1004 |
Decreased/disorganized fibril network of dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA1003 |
Wrinkles |
Physiological |
skin |
Human |
— |
— |
|
| DAA1000 |
Decline in epidermis keratinocyte turnover |
Physiological |
epidermis |
Human |
— |
— |
|