| DAA1000 |
Decline in epidermis keratinocyte turnover |
Physiological |
epidermis |
Human |
— |
— |
|
| DAA1998 |
Lipid oxidation increased with age in males |
Molecular |
skin |
Human |
— |
— |
|
| DAA1997 |
DNA damage increases with age |
Molecular |
skin |
Human |
— |
— |
|
| DAA993 |
Epidermis held less tightly to dermis |
Physiological |
epidermis |
Human |
— |
— |
|
| DAA877 |
Higher oxidation and decreased proteasome activity |
Molecular |
epidermis |
Human |
— |
— |
|
| DAA1004 |
Decreased/disorganized fibril network of dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA618 |
Acute rheumatic fever and chronic rheumatic heart diseases |
Pathological |
heart, skin, brain |
Human |
— |
SeriesMorbidity |
|
| DAA992 |
Decrease in dermal papillae density |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA992 |
Decrease in dermal papillae density |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA1009 |
Dermal collagen atrophies |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2587 |
Hair greying |
Physiological |
hair |
Human |
— |
— |
|
| DAA997 |
Elastin fibers lost from upper layers of dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA1006 |
Decreased amounts of collagen IV and VII, and abnormal elastin in dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA995 |
Change in weave of dermis collagen fibers |
Physiological |
dermis |
Human |
— |
— |
|
| DAA1011 |
Changes in glycosaminoglycan/proteoglycan |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA1011 |
Changes in glycosaminoglycan/proteoglycan |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA996 |
Changes to dermis collagen fiber bundles |
Physiological |
dermis |
Human |
— |
— |
|
| DAA1001 |
Atrophy of hypodermal layer |
Physiological |
subcutaneous |
Human |
— |
— |
|
| DAA2051 |
Attenuated vasoconstriction response to cold |
Physiological |
skin |
Human |
— |
— |
|
| DAA1002 |
Decreased ability to modulate heat loss |
Physiological |
integument system |
Human |
— |
— |
|
| DAA2588 |
Depletion of hair follicle melanocytes |
Physiological |
hair follicle |
Human |
— |
— |
|
| DAA991 |
Decreased function of epithelial barriers |
Physiological |
lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis |
Human |
— |
— |
|
| DAA998 |
Changes to elastin fibers in lower dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2589 |
Male baldness |
Physiological |
hair |
Human |
— |
— |
|
| DAA1005 |
Loss of smooth padding provided by hypodermal fat cells |
Physiological |
skin |
Human |
— |
— |
|