nuclear receptor subfamily 1, group D, member 2
Symbol
NR1D2
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| Eip78C | Drosophila melanogaster | |
| nr1d2b | Danio rerio | |
| Nr1d2 | Mus musculus | |
| Nr1d2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2857 | Gene expression of NR1D2 decreases with age | Molecular | adipose tissue | Human | NR1D2 | — |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-dependent | biological_process | |
| GO:0010467 | gene expression | biological_process | |
| GO:0030522 | intracellular receptor mediated signaling pathway | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005654 | nucleoplasm | cellular_component | |
| GO:0003700 | sequence-specific DNA binding transcription factor activity | molecular_function | |
| GO:0003707 | steroid hormone receptor activity | molecular_function | |
| GO:0004872 | receptor activity | molecular_function | |
| GO:0004879 | ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity | molecular_function | |
| GO:0008270 | zinc ion binding | molecular_function | |
| GO:0043565 | sequence-specific DNA binding | molecular_function | |
| GO:0046872 | metal ion binding | molecular_function | |