ATPase inhibitory factor 1

Symbol

ATPIF1 (may also be known as: None)

Organism

Human

Description

This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
mai-1 Caenorhabditis elegans
CG11079 Drosophila melanogaster
atpif1b Danio rerio
Atpif1 Mus musculus
uncharacterized_M0RB Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA4267 Gene expression of ATPIF1 increases with age Molecular skin Human ATPIF1 —

GO Terms

GO IDGO TermGO Category
GO:0001525 angiogenesis biological_process
GO:0001937 negative regulation of endothelial cell proliferation biological_process
GO:0006091 generation of precursor metabolites and energy biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0043086 negative regulation of catalytic activity biological_process
GO:0045980 negative regulation of nucleotide metabolic process biological_process
GO:0051260 protein homooligomerization biological_process
GO:0051289 protein homotetramerization biological_process
GO:0051346 negative regulation of hydrolase activity biological_process
GO:0072593 reactive oxygen species metabolic process biological_process
GO:0005739 mitochondrion cellular_component
GO:0005753 mitochondrial proton-transporting ATP synthase complex cellular_component
GO:0009986 cell surface cellular_component
GO:0004857 enzyme inhibitor activity molecular_function
GO:0005516 calmodulin binding molecular_function
GO:0042030 ATPase inhibitor activity molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0043532 angiostatin binding molecular_function
GO:0051117 ATPase binding molecular_function