palmitoyl-protein thioesterase 2
Symbol
PPT2
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the palmitoyl-protein thioesterase family. The encoded glycosylated lysosomal protein has palmitoyl-CoA hydrolase activity in vitro, but does not hydrolyze palmitate from cysteine residues in proteins. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain, multiple 8) gene. [provided by RefSeq, Feb 2011]
Orthologs
| Symbol | Species | |
|---|---|---|
| Ppt2 | Drosophila melanogaster | |
| ppt2 | Danio rerio | |
| Ppt2 | Mus musculus | |
| Ppt2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006464 | protein modification process | biological_process | |
| GO:0008152 | metabolic process | biological_process | |
| GO:0005764 | lysosome | cellular_component | |
| GO:0005783 | endoplasmic reticulum | cellular_component | |
| GO:0008474 | palmitoyl-(protein) hydrolase activity | molecular_function | |
| GO:0016787 | hydrolase activity | molecular_function | |
| GO:0016790 | thiolester hydrolase activity | molecular_function | |