solute carrier family 16 (monocarboxylate transporter), member 5
Symbol
SLC16A5
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Orthologs
| Symbol | Species | |
|---|---|---|
| LOC794371 | Danio rerio | |
| Slc16a5 | Mus musculus | |
| Slc16a5 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0015711 | organic anion transport | biological_process | |
| GO:0015718 | monocarboxylic acid transport | biological_process | |
| GO:0055085 | transmembrane transport | biological_process | |
| GO:0005624 | membrane fraction | cellular_component | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0005887 | integral to plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0008028 | monocarboxylic acid transmembrane transporter activity | molecular_function | |
| GO:0015293 | symporter activity | molecular_function | |
| GO:0015355 | secondary active monocarboxylate transmembrane transporter activity | molecular_function | |