wingless-type MMTV integration site family, member 3A

Symbol

WNT3A (may also be known as: None)

Organism

Human

Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
Wnt3a Mus musculus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA4226 Gene expression of WNT3A increases with age Molecular skin Human WNT3A —

GO Terms

GO IDGO TermGO Category
GO:0001649 osteoblast differentiation biological_process
GO:0001701 in utero embryonic development biological_process
GO:0001756 somitogenesis biological_process
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0001947 heart looping biological_process
GO:0002092 positive regulation of receptor internalization biological_process
GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway biological_process
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway biological_process
GO:0007267 cell-cell signaling biological_process
GO:0007275 multicellular organismal development biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0007409 axonogenesis biological_process
GO:0007411 axon guidance biological_process
GO:0007498 mesoderm development biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0009653 anatomical structure morphogenesis biological_process
GO:0009798 axis specification biological_process
GO:0009880 embryonic pattern specification biological_process
GO:0010387 signalosome assembly biological_process
GO:0010977 negative regulation of neuron projection development biological_process
GO:0021527 spinal cord association neuron differentiation biological_process
GO:0021766 hippocampus development biological_process
GO:0021846 cell proliferation in forebrain biological_process
GO:0021874 Wnt receptor signaling pathway involved in forebrain neuroblast division biological_process
GO:0021904 dorsal/ventral neural tube patterning biological_process
GO:0030182 neuron differentiation biological_process
GO:0030198 extracellular matrix organization biological_process
GO:0030879 mammary gland development biological_process
GO:0030890 positive regulation of B cell proliferation biological_process
GO:0030903 notochord development biological_process
GO:0030917 midbrain-hindbrain boundary development biological_process
GO:0032092 positive regulation of protein binding biological_process
GO:0033138 positive regulation of peptidyl-serine phosphorylation biological_process
GO:0034613 cellular protein localization biological_process
GO:0035121 tail morphogenesis biological_process
GO:0035413 positive regulation of catenin import into nucleus biological_process
GO:0042472 inner ear morphogenesis biological_process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:0045595 regulation of cell differentiation biological_process
GO:0045599 negative regulation of fat cell differentiation biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0048103 somatic stem cell division biological_process
GO:0048343 paraxial mesodermal cell fate commitment biological_process
GO:0048697 positive regulation of collateral sprouting in absence of injury biological_process
GO:0048843 negative regulation of axon extension involved in axon guidance biological_process
GO:0050768 negative regulation of neurogenesis biological_process
GO:0050770 regulation of axonogenesis biological_process
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity biological_process
GO:0060021 palate development biological_process
GO:0060026 convergent extension biological_process
GO:0060070 canonical Wnt receptor signaling pathway biological_process
GO:0061098 positive regulation of protein tyrosine kinase activity biological_process
GO:0061184 positive regulation of dermatome development biological_process
GO:0070507 regulation of microtubule cytoskeleton organization biological_process
GO:0070527 platelet aggregation biological_process
GO:0071300 cellular response to retinoic acid biological_process
GO:0071425 hemopoietic stem cell proliferation biological_process
GO:0090245 axis elongation involved in somitogenesis biological_process
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway biological_process
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin biological_process
GO:2000081 positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation biological_process
GO:0005576 extracellular region cellular_component
GO:0005578 proteinaceous extracellular matrix cellular_component
GO:0005615 extracellular space cellular_component
GO:0005769 early endosome cellular_component
GO:0005770 late endosome cellular_component
GO:0005886 plasma membrane cellular_component
GO:0009986 cell surface cellular_component
GO:0045121 membrane raft cellular_component
GO:0003713 transcription coactivator activity molecular_function
GO:0005110 frizzled-2 binding molecular_function
GO:0005201 extracellular matrix structural constituent molecular_function
GO:0005515 protein binding molecular_function
GO:0019904 protein domain specific binding molecular_function
GO:0048018 receptor agonist activity molecular_function