syntaxin 16

Symbol

STX16 (may also be known as: None)

Organism

Human

Description

This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene. [provided by RefSeq, Mar 2011]

Orthologs

SymbolSpecies
Stx16 Mus musculus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006886 intracellular protein transport biological_process
GO:0006891 intra-Golgi vesicle-mediated transport biological_process
GO:0016192 vesicle-mediated transport biological_process
GO:0042147 retrograde transport, endosome to Golgi biological_process
GO:0000139 Golgi membrane cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005792 microsome cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0031201 SNARE complex cellular_component
GO:0005484 SNAP receptor activity molecular_function
GO:0005515 protein binding molecular_function