frizzled class receptor 9

Symbol

FZD9 (may also be known as: None)

Organism

Human

Description

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
cfz-2 Caenorhabditis elegans
fzd9a Danio rerio
Fzd9 Mus musculus
Fzd9 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3486 Gene expression of FZD9 decreases with age Molecular skin Human FZD9 —

GO Terms

GO IDGO TermGO Category
GO:0001944 vasculature development biological_process
GO:0007399 nervous system development biological_process
GO:0007405 neuroblast proliferation biological_process
GO:0007420 brain development biological_process
GO:0007611 learning or memory biological_process
GO:0008406 gonad development biological_process
GO:0009790 embryo development biological_process
GO:0030183 B cell differentiation biological_process
GO:0060070 canonical Wnt receptor signaling pathway biological_process
GO:0005737 cytoplasm cellular_component
GO:0005886 plasma membrane cellular_component
GO:0009986 cell surface cellular_component
GO:0016021 integral to membrane cellular_component
GO:0031527 filopodium membrane cellular_component
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0004871 signal transducer activity molecular_function
GO:0004872 receptor activity molecular_function
GO:0004930 G-protein coupled receptor activity molecular_function
GO:0017147 Wnt-protein binding molecular_function
GO:0030165 PDZ domain binding molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0042813 Wnt-activated receptor activity molecular_function
GO:0046982 protein heterodimerization activity molecular_function