patatin-like phospholipase domain containing 3
Symbol
PNPLA3
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| C05D11.7 | Caenorhabditis elegans | |
| Pnpla3 | Mus musculus | |
| Pnpla3 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2930 | Gene expression of PNPLA3 decreases with age | Molecular | adipose tissue | Human | PNPLA3 | — |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0008152 | metabolic process | biological_process | |
| GO:0016042 | lipid catabolic process | biological_process | |
| GO:0019432 | triglyceride biosynthetic process | biological_process | |
| GO:0019433 | triglyceride catabolic process | biological_process | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0004623 | phospholipase A2 activity | molecular_function | |
| GO:0004806 | triglyceride lipase activity | molecular_function | |
| GO:0016746 | transferase activity, transferring acyl groups | molecular_function | |
| GO:0016787 | hydrolase activity | molecular_function | |
| GO:0051264 | mono-olein transacylation activity | molecular_function | |
| GO:0051265 | diolein transacylation activity | molecular_function | |