adiponectin receptor 2
Symbol
ADIPOR2
(may also be known as: None)
Organism
Human
Description
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| adipor2 | Danio rerio | |
| Adipor2 | Mus musculus | |
| Adipor2 | Rattus norvegicus | |
| SPBC12C2.09c | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | biological_process | |
| GO:0009755 | hormone-mediated signaling pathway | biological_process | |
| GO:0019395 | fatty acid oxidation | biological_process | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0004872 | receptor activity | molecular_function | |
| GO:0042562 | hormone binding | molecular_function | |
| GO:0042802 | identical protein binding | molecular_function | |
| GO:0046982 | protein heterodimerization activity | molecular_function | |