matrix metallopeptidase 28

Symbol

MMP28 (may also be known as: None)

Organism

Human

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Orthologs

SymbolSpecies
LOC100005670 Danio rerio
Mmp28 Mus musculus
Mmp28 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA4113 Gene expression of MMP28 increases with age Molecular skin Human MMP28 —

GO Terms

GO IDGO TermGO Category
GO:0006508 proteolysis biological_process
GO:0008152 metabolic process biological_process
GO:0005576 extracellular region cellular_component
GO:0005578 proteinaceous extracellular matrix cellular_component
GO:0031012 extracellular matrix cellular_component
GO:0004222 metalloendopeptidase activity molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008270 zinc ion binding molecular_function