vasoactive intestinal peptide receptor 1
Symbol
VIPR1
(may also be known as: None)
Organism
Human
Description
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Orthologs
| Symbol | Species | |
|---|---|---|
| vipr1a | Danio rerio | |
| Vipr1 | Mus musculus | |
| Vipr1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006936 | muscle contraction | biological_process | |
| GO:0006955 | immune response | biological_process | |
| GO:0007186 | G-protein coupled receptor signaling pathway | biological_process | |
| GO:0007187 | G-protein signaling, coupled to cyclic nucleotide second messenger | biological_process | |
| GO:0007268 | synaptic transmission | biological_process | |
| GO:0007586 | digestion | biological_process | |
| GO:0008284 | positive regulation of cell proliferation | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005730 | nucleolus | cellular_component | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0005887 | integral to plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0004871 | signal transducer activity | molecular_function | |
| GO:0004872 | receptor activity | molecular_function | |
| GO:0004999 | vasoactive intestinal polypeptide receptor activity | molecular_function | |