UDP glucuronosyltransferase 2 family, polypeptide B17

Symbol

UGT2B17 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.[provided by RefSeq, Apr 2010]

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3455 Gene expression of UGT2B17 decreases with age Molecular skin Human UGT2B17 —

GO Terms

GO IDGO TermGO Category
GO:0008152 metabolic process biological_process
GO:0008202 steroid metabolic process biological_process
GO:0005624 membrane fraction cellular_component
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0005792 microsome cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0001972 retinoic acid binding molecular_function
GO:0015020 glucuronosyltransferase activity molecular_function