complement component 3

Symbol

C3 (may also be known as: CPAMD1)

Organism

Human

Orthologs

SymbolSpecies
LOC100331428 Danio rerio
C3 Mus musculus
C3 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA487 complement component 3 Molecular skeletal muscle Human C3 16.0% Increase Gene Expression Level
DAA2174 complement component 3 increases with age Molecular hippocampus Human C3 201.6% Increase Gene Expression Level
DAA2186 complement component 3 increases with age Molecular parietal lobe Human C3 108.4% Increase Gene Expression Level

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1527 complement component 3 Molecular liver Mouse C3 5.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0001798 positive regulation of type IIa hypersensitivity biological_process
GO:0001970 positive regulation of activation of membrane attack complex biological_process
GO:0006954 inflammatory response biological_process
GO:0006955 immune response biological_process
GO:0006956 complement activation biological_process
GO:0006957 complement activation, alternative pathway biological_process
GO:0006958 complement activation, classical pathway biological_process
GO:0007165 signal transduction biological_process
GO:0007186 G-protein coupled receptor signaling pathway biological_process
GO:0010575 positive regulation vascular endothelial growth factor production biological_process
GO:0045087 innate immune response biological_process
GO:0045766 positive regulation of angiogenesis biological_process
GO:0050766 positive regulation of phagocytosis biological_process
GO:0050776 regulation of immune response biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0004866 endopeptidase inhibitor activity molecular_function
GO:0005102 receptor binding molecular_function
GO:0005515 protein binding molecular_function