trichohyalin

Symbol

TCHH (may also be known as: None)

Organism

Human

Description

Trichohyalin confers mechanical strength to the hair follicle inner root sheath and to other toughened epithelial tissues, such as the hard palate and filiform ridges of the tongue, by forming multiple complex crosslinks with itself and with other structural proteins (Steinert et al., 2003 [PubMed 12853460]).[supplied by OMIM, Dec 2009]

Links to external resources

Entrez Gene: 7062
OMIM: 190370
Ensembl: ENSG00000159450
UniProt: Q07283
UniGene: Hs.432416
GeneCards

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA3433	Gene expression of TCHH decreases with age	Molecular	skin	Human	TCHH	—

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GO Terms

GO ID	GO Term	GO Category
GO:0008150	biological_process	biological_process
GO:0031424	keratinization	biological_process
GO:0005737	cytoplasm	cellular_component
GO:0005813	centrosome	cellular_component
GO:0005856	cytoskeleton	cellular_component
GO:0005886	plasma membrane	cellular_component
GO:0045111	intermediate filament cytoskeleton	cellular_component
GO:0005509	calcium ion binding	molecular_function