spermidine synthase
Symbol
SRM
(may also be known as: None)
Organism
Human
Description
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| spds-1 | Caenorhabditis elegans | |
| SpdS | Drosophila melanogaster | |
| srm | Danio rerio | |
| Srm | Mus musculus | |
| LOC100364487 | Rattus norvegicus | |
| SPE3 | Saccharomyces cerevisiae | |
| SPBC12C2.07c | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006595 | polyamine metabolic process | biological_process | |
| GO:0008295 | spermidine biosynthetic process | biological_process | |
| GO:0034641 | cellular nitrogen compound metabolic process | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0005829 | cytosol | cellular_component | |
| GO:0004766 | spermidine synthase activity | molecular_function | |
| GO:0016740 | transferase activity | molecular_function | |
| GO:0042803 | protein homodimerization activity | molecular_function | |