chemokine (C-X-C motif) ligand 5
Symbol
CXCL5
(may also be known as: None)
Organism
Human
Description
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]
Orthologs
| Symbol | Species | |
|---|---|---|
| Cxcl5 | Mus musculus | |
| Cxcl5 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2299 | chemokine (C-X-C motif) ligand 5 increases with age | Molecular | hippocampus | Human | CXCL5 | 64.9% Increase Gene Expression Level |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006935 | chemotaxis | biological_process | |
| GO:0006955 | immune response | biological_process | |
| GO:0007165 | signal transduction | biological_process | |
| GO:0007267 | cell-cell signaling | biological_process | |
| GO:0008284 | positive regulation of cell proliferation | biological_process | |
| GO:0005576 | extracellular region | cellular_component | |
| GO:0005615 | extracellular space | cellular_component | |
| GO:0008009 | chemokine activity | molecular_function | |