methylsterol monooxygenase 1
Symbol
MSMO1
(may also be known as: None)
Organism
Human
Description
Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| msmo1 | Danio rerio | |
| Msmo1 | Mus musculus | |
| Msmo1 | Rattus norvegicus | |
| ERG25 | Saccharomyces cerevisiae | |
| erg25 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006631 | fatty acid metabolic process | biological_process | |
| GO:0006633 | fatty acid biosynthetic process | biological_process | |
| GO:0006695 | cholesterol biosynthetic process | biological_process | |
| GO:0008202 | steroid metabolic process | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0005783 | endoplasmic reticulum | cellular_component | |
| GO:0005789 | endoplasmic reticulum membrane | cellular_component | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0000254 | C-4 methylsterol oxidase activity | molecular_function | |
| GO:0005506 | iron ion binding | molecular_function | |
| GO:0016491 | oxidoreductase activity | molecular_function | |