S100 calcium binding protein A9

Symbol

S100A9 (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
S100a9 Mus musculus
S100a9 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2244 S100 calcium binding protein A9 increases with age Molecular frontal lobe Human S100A9 92.8% Increase Gene Expression Level
DAA2232 S100 calcium binding protein A9 increases with age Molecular parietal lobe Human S100A9 229.0% Increase Gene Expression Level

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1431 S100 calcium binding protein A9 (calgranulin B) Molecular hippocampus Mouse S100a9 33.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0002544 chronic inflammatory response biological_process
GO:0006935 chemotaxis biological_process
GO:0006954 inflammatory response biological_process
GO:0007165 signal transduction biological_process
GO:0007267 cell-cell signaling biological_process
GO:0010043 response to zinc ion biological_process
GO:0030595 leukocyte chemotaxis biological_process
GO:0031532 actin cytoskeleton reorganization biological_process
GO:0032496 response to lipopolysaccharide biological_process
GO:0045113 regulation of integrin biosynthetic process biological_process
GO:0045471 response to ethanol biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005634 nucleus cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005886 plasma membrane cellular_component
GO:0004871 signal transducer activity molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0005515 protein binding molecular_function