S100 calcium binding protein A9
Symbol
S100A9
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]
Orthologs
Symbol | Species | |
---|---|---|
S100a9 | Mus musculus | |
S100a9 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
---|---|---|---|---|---|---|---|
DAA2244 | S100 calcium binding protein A9 increases with age | Molecular | frontal lobe | Human | S100A9 | 92.8% Increase Gene Expression Level | |
DAA2232 | S100 calcium binding protein A9 increases with age | Molecular | parietal lobe | Human | S100A9 | 229.0% Increase Gene Expression Level |
Changes associated with the orthologs of this gene
Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
---|---|---|---|---|---|---|---|
DAA1431 | S100 calcium binding protein A9 (calgranulin B) | Molecular | hippocampus | Mouse | S100a9 | 33.0% Increase Gene Expression Level |
GO Terms
GO ID | GO Term | GO Category | |
---|---|---|---|
GO:0002544 | chronic inflammatory response | biological_process | |
GO:0006935 | chemotaxis | biological_process | |
GO:0006954 | inflammatory response | biological_process | |
GO:0007165 | signal transduction | biological_process | |
GO:0007267 | cell-cell signaling | biological_process | |
GO:0010043 | response to zinc ion | biological_process | |
GO:0030595 | leukocyte chemotaxis | biological_process | |
GO:0031532 | actin cytoskeleton reorganization | biological_process | |
GO:0032496 | response to lipopolysaccharide | biological_process | |
GO:0045113 | regulation of integrin biosynthetic process | biological_process | |
GO:0045471 | response to ethanol | biological_process | |
GO:0005576 | extracellular region | cellular_component | |
GO:0005615 | extracellular space | cellular_component | |
GO:0005634 | nucleus | cellular_component | |
GO:0005730 | nucleolus | cellular_component | |
GO:0005737 | cytoplasm | cellular_component | |
GO:0005856 | cytoskeleton | cellular_component | |
GO:0005886 | plasma membrane | cellular_component | |
GO:0004871 | signal transducer activity | molecular_function | |
GO:0005509 | calcium ion binding | molecular_function | |
GO:0005515 | protein binding | molecular_function | |