branched chain amino-acid transaminase 2, mitochondrial

Symbol

BCAT2 (may also be known as: None)

Organism

Human

Description

This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Orthologs

SymbolSpecies
bcat-1 Caenorhabditis elegans
CG1673 Drosophila melanogaster
Bcat2 Mus musculus
Bcat2 Rattus norvegicus
BAT1 Saccharomyces cerevisiae
eca39 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3007 Gene expression of BCAT2 decreases with age Molecular skin Human BCAT2 —

GO Terms

GO IDGO TermGO Category
GO:0006550 isoleucine catabolic process biological_process
GO:0006573 valine metabolic process biological_process
GO:0007595 lactation biological_process
GO:0009082 branched chain family amino acid biosynthetic process biological_process
GO:0009083 branched chain family amino acid catabolic process biological_process
GO:0009098 leucine biosynthetic process biological_process
GO:0010817 regulation of hormone levels biological_process
GO:0034641 cellular nitrogen compound metabolic process biological_process
GO:0044281 small molecule metabolic process biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005759 mitochondrial matrix cellular_component
GO:0004084 branched-chain-amino-acid transaminase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0052654 L-leucine transaminase activity molecular_function
GO:0052655 L-valine transaminase activity molecular_function
GO:0052656 L-isoleucine transaminase activity molecular_function