isoprenylcysteine carboxyl methyltransferase

Symbol

Icmt (may also be known as: PPMT, STE1)

Organism

Mouse

Orthologs

SymbolSpecies
CELE_M01E11.1 Caenorhabditis elegans
ste14 Drosophila melanogaster
icmt Danio rerio
ICMT Homo sapiens
Icmt Rattus norvegicus
STE14 Saccharomyces cerevisiae
mam4 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1562 isoprenylcysteine carboxyl methyltransferase Molecular lung Mouse Icmt 3.0% Decrease Gene Expression Level

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3729 Gene expression of ICMT decreases with age Molecular skin Human ICMT —

GO Terms

GO IDGO TermGO Category
GO:0001701 in utero embryonic development biological_process
GO:0001889 liver development biological_process
GO:0006479 protein methylation biological_process
GO:0006481 C-terminal protein methylation biological_process
GO:0008104 protein localization biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0032259 methylation biological_process
GO:0035264 multicellular organism growth biological_process
GO:0046498 S-adenosylhomocysteine metabolic process biological_process
GO:0046499 S-adenosylmethioninamine metabolic process biological_process
GO:0046578 regulation of Ras protein signal transduction biological_process
GO:2001141 regulation of RNA biosynthetic process biological_process
GO:0005624 membrane fraction cellular_component
GO:0005783 endoplasmic reticulum cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity molecular_function
GO:0008140 cAMP response element binding protein binding molecular_function
GO:0008168 methyltransferase activity molecular_function
GO:0016740 transferase activity molecular_function