aarF domain containing kinase 3

Symbol

ADCK3 (may also be known as: None)

Organism

Human

Description

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
CG4410 Drosophila melanogaster
adck3 Danio rerio
Adck3 Mus musculus
Adck3 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0008219 cell death biological_process
GO:0005739 mitochondrion cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0016301 kinase activity molecular_function