chemokine (C-C motif) ligand 28
Symbol
CCL28
(may also be known as: None)
Organism
Human
Description
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Ccl28 | Mus musculus | |
| Ccl28 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0006935 | chemotaxis | biological_process |
| GO:0006955 | immune response | biological_process |
| GO:0007204 | elevation of cytosolic calcium ion concentration | biological_process |
| GO:0005576 | extracellular region | cellular_component |
| GO:0005615 | extracellular space | cellular_component |
| GO:0008009 | chemokine activity | molecular_function |