mitogen-activated protein kinase 1

Symbol

MAPK1 (may also be known as: ERK, ERK2,)

Organism

Human

Orthologs

SymbolSpecies
mapk1 Danio rerio
Mapk1 Mus musculus
Mapk1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA131 mitogen-activated protein kinase 1 Molecular brain Human MAPK1 17.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000165 MAPKKK cascade biological_process
GO:0000186 activation of MAPKK activity biological_process
GO:0000187 activation of MAPK activity biological_process
GO:0000189 MAPK import into nucleus biological_process
GO:0002224 toll-like receptor signaling pathway biological_process
GO:0002755 MyD88-dependent toll-like receptor signaling pathway biological_process
GO:0002756 MyD88-independent toll-like receptor signaling pathway biological_process
GO:0006915 apoptotic process biological_process
GO:0006917 induction of apoptosis biological_process
GO:0006935 chemotaxis biological_process
GO:0006950 response to stress biological_process
GO:0006974 response to DNA damage stimulus biological_process
GO:0007049 cell cycle biological_process
GO:0007165 signal transduction biological_process
GO:0007173 epidermal growth factor receptor signaling pathway biological_process
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0007265 Ras protein signal transduction biological_process
GO:0007268 synaptic transmission biological_process
GO:0007411 axon guidance biological_process
GO:0007596 blood coagulation biological_process
GO:0008063 Toll signaling pathway biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0008286 insulin receptor signaling pathway biological_process
GO:0008543 fibroblast growth factor receptor signaling pathway biological_process
GO:0009636 response to toxin biological_process
GO:0009887 organ morphogenesis biological_process
GO:0010800 positive regulation of peptidyl-threonine phosphorylation biological_process
GO:0018105 peptidyl-serine phosphorylation biological_process
GO:0019233 sensory perception of pain biological_process
GO:0019858 cytosine metabolic process biological_process
GO:0030168 platelet activation biological_process
GO:0030335 positive regulation of cell migration biological_process
GO:0031663 lipopolysaccharide-mediated signaling pathway biological_process
GO:0032496 response to lipopolysaccharide biological_process
GO:0032872 regulation of stress-activated MAPK cascade biological_process
GO:0033598 mammary gland epithelial cell proliferation biological_process
GO:0034130 toll-like receptor 1 signaling pathway biological_process
GO:0034134 toll-like receptor 2 signaling pathway biological_process
GO:0034138 toll-like receptor 3 signaling pathway biological_process
GO:0034142 toll-like receptor 4 signaling pathway biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0035666 TRIF-dependent toll-like receptor signaling pathway biological_process
GO:0043330 response to exogenous dsRNA biological_process
GO:0043627 response to estrogen stimulus biological_process
GO:0044419 interspecies interaction between organisms biological_process
GO:0045087 innate immune response biological_process
GO:0045596 negative regulation of cell differentiation biological_process
GO:0045727 positive regulation of translation biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0048011 nerve growth factor receptor signaling pathway biological_process
GO:0050852 T cell receptor signaling pathway biological_process
GO:0050853 B cell receptor signaling pathway biological_process
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity biological_process
GO:0051403 stress-activated MAPK cascade biological_process
GO:0051493 regulation of cytoskeleton organization biological_process
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway biological_process
GO:0060716 labyrinthine layer blood vessel development biological_process
GO:0070371 ERK1 and ERK2 cascade biological_process
GO:0072584 caveolin-mediated endocytosis biological_process
GO:0090170 regulation of Golgi inheritance biological_process
GO:2000641 regulation of early endosome to late endosome transport biological_process
GO:0005625 soluble fraction cellular_component
GO:0005626 insoluble fraction cellular_component
GO:0005634 nucleus cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005769 early endosome cellular_component
GO:0005770 late endosome cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0005815 microtubule organizing center cellular_component
GO:0005829 cytosol cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005901 caveola cellular_component
GO:0005925 focal adhesion cellular_component
GO:0031143 pseudopodium cellular_component
GO:0032839 dendrite cytoplasm cellular_component
GO:0033267 axon part cellular_component
GO:0043204 perikaryon cellular_component
GO:0043234 protein complex cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0001784 phosphotyrosine binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004707 MAP kinase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0008134 transcription factor binding molecular_function
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity molecular_function
GO:0019902 phosphatase binding molecular_function
GO:0031435 mitogen-activated protein kinase kinase kinase binding molecular_function