gasdermin B

Symbol

GSDMB (may also be known as: None)

Organism

Human

Description

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Sep 2009]

Links to external resources

Entrez Gene: 55876
OMIM: 611221
Ensembl: ENSG00000073605
UniProt: Q8TAX9
UniGene: Hs.306777
GeneCards

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA3971	Gene expression of GSDMB increases with age	Molecular	skin	Human	GSDMB	—

First
Last

GO Terms

GO ID	GO Term	GO Category
GO:0005737	cytoplasm	cellular_component