DEAD (Asp-Glu-Ala-Asp) box polypeptide 27

Symbol

DDX27 (may also be known as: None)

Organism

Human

Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, the function of which has not been determined. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
Rs1 Drosophila melanogaster
ddx27 Danio rerio
Ddx27 Mus musculus
Ddx27 Rattus norvegicus
DRS1 Saccharomyces cerevisiae
drs1 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0005634 nucleus cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0004386 helicase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0008026 ATP-dependent helicase activity molecular_function
GO:0016787 hydrolase activity molecular_function