piwi-like RNA-mediated gene silencing 2
Symbol
PIWIL2
(may also be known as: None)
Organism
Human
Description
PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| prg-2 | Caenorhabditis elegans | |
| piwil2 | Danio rerio | |
| Piwil2 | Mus musculus | |
| Piwil2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0000966 | RNA 5'-end processing | biological_process | |
| GO:0007126 | meiosis | biological_process | |
| GO:0007128 | meiotic prophase I | biological_process | |
| GO:0007275 | multicellular organismal development | biological_process | |
| GO:0007283 | spermatogenesis | biological_process | |
| GO:0030154 | cell differentiation | biological_process | |
| GO:0030718 | germ-line stem cell maintenance | biological_process | |
| GO:0031047 | gene silencing by RNA | biological_process | |
| GO:0034587 | piRNA metabolic process | biological_process | |
| GO:0043046 | DNA methylation involved in gamete generation | biological_process | |
| GO:0045727 | positive regulation of translation | biological_process | |
| GO:0048477 | oogenesis | biological_process | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005844 | polysome | cellular_component | |
| GO:0033391 | chromatoid body | cellular_component | |
| GO:0043186 | P granule | cellular_component | |
| GO:0071546 | pi-body | cellular_component | |
| GO:0003729 | mRNA binding | molecular_function | |
| GO:0034584 | piRNA binding | molecular_function | |