poly (ADP-ribose) polymerase family, member 14

Symbol

PARP14 (may also be known as: None)

Organism

Human

Description

Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent posttranslational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).[supplied by OMIM, Mar 2008]

Orthologs

SymbolSpecies
LOC100537011 Danio rerio
Parp14 Mus musculus
Parp14 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3898 Gene expression of PARP14 increases with age Molecular skin Human PARP14 —

GO Terms

GO IDGO TermGO Category
GO:0006355 regulation of transcription, DNA-dependent biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005886 plasma membrane cellular_component
GO:0003950 NAD+ ADP-ribosyltransferase activity molecular_function
GO:0016757 transferase activity, transferring glycosyl groups molecular_function