phosphatidylinositol transfer protein, alpha

Symbol

PITPNA (may also be known as: None)

Organism

Human

Description

This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.[provided by RefSeq, Sep 2009]

Orthologs

SymbolSpecies
CELE_Y54F10AR.1 Caenorhabditis elegans
vib Drosophila melanogaster
pitpnab Danio rerio
Pitpna Mus musculus
Pitpna Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2076 phosphatidylinositol transfer protein, alpha increases with age Molecular ovary Human PITPNA 75.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006629 lipid metabolic process biological_process
GO:0006810 transport biological_process
GO:0007411 axon guidance biological_process
GO:0007601 visual perception biological_process
GO:0015914 phospholipid transport biological_process
GO:0005622 intracellular cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005543 phospholipid binding molecular_function
GO:0008525 phosphatidylcholine transporter activity molecular_function
GO:0008526 phosphatidylinositol transporter activity molecular_function