hydroxyacid oxidase 2 (long chain)
Symbol
HAO2
(may also be known as: None)
Organism
Human
Description
This gene is one of three related genes that have 2-hydroxyacid oxidase activity. The encoded protein localizes to the peroxisome has the highest activity toward the substrate 2-hydroxypalmitate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Orthologs
| Symbol | Species | |
|---|---|---|
| hao2 | Danio rerio | |
| Hao2 | Mus musculus | |
| Hao2 | Rattus norvegicus | |
| CYB2 | Saccharomyces cerevisiae | |
| SPAPB1A11.03 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0018924 | mandelate metabolic process | biological_process | |
| GO:0019395 | fatty acid oxidation | biological_process | |
| GO:0051260 | protein homooligomerization | biological_process | |
| GO:0005739 | mitochondrion | cellular_component | |
| GO:0005777 | peroxisome | cellular_component | |
| GO:0003973 | (S)-2-hydroxy-acid oxidase activity | molecular_function | |
| GO:0010181 | FMN binding | molecular_function | |
| GO:0016491 | oxidoreductase activity | molecular_function | |
| GO:0052852 | very-long-chain-(S)-2-hydroxy-acid oxidase activity | molecular_function | |
| GO:0052853 | long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity | molecular_function | |
| GO:0052854 | medium-chain-(S)-2-hydroxy-acid oxidase activity | molecular_function | |