natural killer-tumor recognition sequence
Symbol
NKTR
(may also be known as: None)
Organism
Human
Description
This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| nktr | Danio rerio | |
| Nktr | Mus musculus | |
| LOC100364165 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA3287 | Gene expression of NKTR increases with age | Molecular | skin | Human | NKTR | — | |
| DAA2074 | natural killer-tumor recognition sequence decreases with age | Molecular | ovary | Human | NKTR | 37.5% Decrease Gene Expression Level |
Changes associated with the orthologs of this gene
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0006457 | protein folding | biological_process |
| GO:0016020 | membrane | cellular_component |
| GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | molecular_function |
| GO:0016018 | cyclosporin A binding | molecular_function |
| GO:0016853 | isomerase activity | molecular_function |