NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
Symbol
NDUFA8
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene belongs to the complex I 19 kDA subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| CELE_Y54F10AM.5 | Caenorhabditis elegans | |
| CG3683 | Drosophila melanogaster | |
| ndufa8 | Danio rerio | |
| Ndufa8 | Mus musculus | |
| Ndufa8 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | biological_process | |
| GO:0006810 | transport | biological_process | |
| GO:0022904 | respiratory electron transport chain | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0005739 | mitochondrion | cellular_component | |
| GO:0005743 | mitochondrial inner membrane | cellular_component | |
| GO:0005747 | mitochondrial respiratory chain complex I | cellular_component | |
| GO:0005758 | mitochondrial intermembrane space | cellular_component | |
| GO:0070469 | respiratory chain | cellular_component | |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | molecular_function | |