kallikrein-related peptidase 12
Symbol
KLK12
(may also be known as: None)
Organism
Human
Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Klk12 | Mus musculus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006508 | proteolysis | biological_process | |
| GO:0005576 | extracellular region | cellular_component | |
| GO:0005625 | soluble fraction | cellular_component | |
| GO:0003824 | catalytic activity | molecular_function | |
| GO:0004252 | serine-type endopeptidase activity | molecular_function | |
| GO:0008233 | peptidase activity | molecular_function | |
| GO:0008236 | serine-type peptidase activity | molecular_function | |