low density lipoprotein receptor-related protein 4

Symbol

LRP4 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010]

Orthologs

SymbolSpecies
CG8909 Drosophila melanogaster
Lrp4 Mus musculus
Lrp4 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3253 Gene expression of LRP4 increases with age Molecular skin Human LRP4 —

GO Terms

GO IDGO TermGO Category
GO:0001822 kidney development biological_process
GO:0001942 hair follicle development biological_process
GO:0006897 endocytosis biological_process
GO:0007275 multicellular organismal development biological_process
GO:0008104 protein localization biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0009954 proximal/distal pattern formation biological_process
GO:0030154 cell differentiation biological_process
GO:0030178 negative regulation of Wnt receptor signaling pathway biological_process
GO:0030279 negative regulation of ossification biological_process
GO:0042475 odontogenesis of dentin-containing tooth biological_process
GO:0042733 embryonic digit morphogenesis biological_process
GO:0043113 receptor clustering biological_process
GO:0048856 anatomical structure development biological_process
GO:0051124 synaptic growth at neuromuscular junction biological_process
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway biological_process
GO:0005575 cellular_component cellular_component
GO:0005886 plasma membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0004872 receptor activity molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0005515 protein binding molecular_function