regulator of G protein signaling 9 binding protein
Symbol
RGS9BP
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia. [provided by RefSeq, Mar 2010]
Orthologs
Symbol | Species | |
---|---|---|
si:ch73-167i17.6 | Danio rerio | |
Rgs9bp | Mus musculus | |
Rgs9bp | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
GO ID | GO Term | GO Category |
---|---|---|
GO:0009968 | negative regulation of signal transduction | biological_process |
GO:0050896 | response to stimulus | biological_process |
GO:0050908 | detection of light stimulus involved in visual perception | biological_process |
GO:0016020 | membrane | cellular_component |
GO:0016021 | integral to membrane | cellular_component |