regulator of G protein signaling 9 binding protein

Symbol

RGS9BP (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia. [provided by RefSeq, Mar 2010]

Orthologs

SymbolSpecies
si:ch73-167i17.6 Danio rerio
Rgs9bp Mus musculus
Rgs9bp Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0009968 negative regulation of signal transduction biological_process
GO:0050896 response to stimulus biological_process
GO:0050908 detection of light stimulus involved in visual perception biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component