potassium large conductance calcium-activated channel, subfamily M, beta member 1
Symbol
KCNMB1
(may also be known as: None)
Organism
Human
Description
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Kcnmb1 | Mus musculus | |
| Kcnmb1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006811 | ion transport | biological_process | |
| GO:0006813 | potassium ion transport | biological_process | |
| GO:0007268 | synaptic transmission | biological_process | |
| GO:0007596 | blood coagulation | biological_process | |
| GO:0051592 | response to calcium ion | biological_process | |
| GO:0071805 | potassium ion transmembrane transport | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0008076 | voltage-gated potassium channel complex | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0005216 | ion channel activity | molecular_function | |
| GO:0005267 | potassium channel activity | molecular_function | |
| GO:0015269 | calcium-activated potassium channel activity | molecular_function | |
| GO:0015459 | potassium channel regulator activity | molecular_function | |