potassium channel, subfamily K, member 2
Symbol
KCNK2
(may also be known as: None)
Organism
Human
Description
This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Ork1 | Drosophila melanogaster | |
| LOC559728 | Danio rerio | |
| Kcnk2 | Mus musculus | |
| Kcnk2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006811 | ion transport | biological_process | |
| GO:0006813 | potassium ion transport | biological_process | |
| GO:0007186 | G-protein coupled receptor signaling pathway | biological_process | |
| GO:0007268 | synaptic transmission | biological_process | |
| GO:0071805 | potassium ion transmembrane transport | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0008076 | voltage-gated potassium channel complex | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0005216 | ion channel activity | molecular_function | |
| GO:0005244 | voltage-gated ion channel activity | molecular_function | |
| GO:0005249 | voltage-gated potassium channel activity | molecular_function | |
| GO:0005267 | potassium channel activity | molecular_function | |
| GO:0015271 | outward rectifier potassium channel activity | molecular_function | |