jagged 2
Symbol
JAG2
(may also be known as: None)
Organism
Human
Description
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| jag2 | Danio rerio | |
| Jag2 | Mus musculus | |
| Jag2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0001501 | skeletal system development | biological_process | |
| GO:0001701 | in utero embryonic development | biological_process | |
| GO:0003016 | respiratory system process | biological_process | |
| GO:0007049 | cell cycle | biological_process | |
| GO:0007154 | cell communication | biological_process | |
| GO:0007219 | Notch signaling pathway | biological_process | |
| GO:0007220 | Notch receptor processing | biological_process | |
| GO:0007275 | multicellular organismal development | biological_process | |
| GO:0007283 | spermatogenesis | biological_process | |
| GO:0009912 | auditory receptor cell fate commitment | biological_process | |
| GO:0016331 | morphogenesis of embryonic epithelium | biological_process | |
| GO:0030154 | cell differentiation | biological_process | |
| GO:0030155 | regulation of cell adhesion | biological_process | |
| GO:0030217 | T cell differentiation | biological_process | |
| GO:0030334 | regulation of cell migration | biological_process | |
| GO:0042127 | regulation of cell proliferation | biological_process | |
| GO:0042475 | odontogenesis of dentin-containing tooth | biological_process | |
| GO:0042981 | regulation of apoptotic process | biological_process | |
| GO:0045061 | thymic T cell selection | biological_process | |
| GO:0005624 | membrane fraction | cellular_component | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0005887 | integral to plasma membrane | cellular_component | |
| GO:0005112 | Notch binding | molecular_function | |
| GO:0005509 | calcium ion binding | molecular_function | |
| GO:0005515 | protein binding | molecular_function | |
| GO:0008083 | growth factor activity | molecular_function | |