insulin receptor

Symbol

INSR (may also be known as: CD220)

Organism

Human

Orthologs

SymbolSpecies
insrb Danio rerio
Insr Mus musculus
Insr Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA109 insulin receptor Molecular brain Human INSR 8.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000187 activation of MAPK activity biological_process
GO:0001933 negative regulation of protein phosphorylation biological_process
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0003007 heart morphogenesis biological_process
GO:0005975 carbohydrate metabolic process biological_process
GO:0006355 regulation of transcription, DNA-dependent biological_process
GO:0007186 G-protein coupled receptor signaling pathway biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0008286 insulin receptor signaling pathway biological_process
GO:0009725 response to hormone stimulus biological_process
GO:0009749 response to glucose stimulus biological_process
GO:0009887 organ morphogenesis biological_process
GO:0010042 response to manganese ion biological_process
GO:0010310 regulation of hydrogen peroxide metabolic process biological_process
GO:0010560 positive regulation of glycoprotein biosynthetic process biological_process
GO:0010629 negative regulation of gene expression biological_process
GO:0014823 response to activity biological_process
GO:0018108 peptidyl-tyrosine phosphorylation biological_process
GO:0019087 transformation of host cell by virus biological_process
GO:0023014 signal transduction via phosphorylation event biological_process
GO:0030238 male sex determination biological_process
GO:0030335 positive regulation of cell migration biological_process
GO:0031017 exocrine pancreas development biological_process
GO:0031667 response to nutrient levels biological_process
GO:0032147 activation of protein kinase activity biological_process
GO:0032148 activation of protein kinase B activity biological_process
GO:0032355 response to estradiol stimulus biological_process
GO:0032410 negative regulation of transporter activity biological_process
GO:0032868 response to insulin stimulus biological_process
GO:0032869 cellular response to insulin stimulus biological_process
GO:0033280 response to vitamin D biological_process
GO:0033574 response to testosterone stimulus biological_process
GO:0034612 response to tumor necrosis factor biological_process
GO:0042327 positive regulation of phosphorylation biological_process
GO:0042593 glucose homeostasis biological_process
GO:0043410 positive regulation of MAPKKK cascade biological_process
GO:0045429 positive regulation of nitric oxide biosynthetic process biological_process
GO:0045444 fat cell differentiation biological_process
GO:0045471 response to ethanol biological_process
GO:0045725 positive regulation of glycogen biosynthetic process biological_process
GO:0045740 positive regulation of DNA replication biological_process
GO:0045821 positive regulation of glycolysis biological_process
GO:0045840 positive regulation of mitosis biological_process
GO:0045995 regulation of embryonic development biological_process
GO:0046326 positive regulation of glucose import biological_process
GO:0046777 protein autophosphorylation biological_process
GO:0048639 positive regulation of developmental growth biological_process
GO:0051290 protein heterotetramerization biological_process
GO:0051384 response to glucocorticoid stimulus biological_process
GO:0051897 positive regulation of protein kinase B signaling cascade biological_process
GO:0060267 positive regulation of respiratory burst biological_process
GO:0071363 cellular response to growth factor stimulus biological_process
GO:0005625 soluble fraction cellular_component
GO:0005634 nucleus cellular_component
GO:0005768 endosome cellular_component
GO:0005792 microsome cellular_component
GO:0005829 cytosol cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0005899 insulin receptor complex cellular_component
GO:0005901 caveola cellular_component
GO:0010008 endosome membrane cellular_component
GO:0016020 membrane cellular_component
GO:0045202 synapse cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function
GO:0004716 receptor signaling protein tyrosine kinase activity molecular_function
GO:0004872 receptor activity molecular_function
GO:0005009 insulin-activated receptor activity molecular_function
GO:0005159 insulin-like growth factor receptor binding molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0005525 GTP binding molecular_function
GO:0019903 protein phosphatase binding molecular_function
GO:0019904 protein domain specific binding molecular_function
GO:0031405 lipoic acid binding molecular_function
GO:0031994 insulin-like growth factor I binding molecular_function
GO:0031995 insulin-like growth factor II binding molecular_function
GO:0032403 protein complex binding molecular_function
GO:0042169 SH2 domain binding molecular_function
GO:0043423 3-phosphoinositide-dependent protein kinase binding molecular_function
GO:0043548 phosphatidylinositol 3-kinase binding molecular_function
GO:0043559 insulin binding molecular_function
GO:0043560 insulin receptor substrate binding molecular_function
GO:0051425 PTB domain binding molecular_function