interleukin 6 (interferon, beta 2)

Symbol

IL6

Organism

Human

Orthologs

Symbol	Species
Il6	Mus musculus
Il6	Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA1209	Blood IL6 level increase	Physiological	plasma	Human	IL6	—

First
Last

GO Terms

GO ID	GO Term	GO Category
GO:0001781	neutrophil apoptosis	biological_process
GO:0002384	hepatic immune response	biological_process
GO:0002446	neutrophil mediated immunity	biological_process
GO:0002548	monocyte chemotaxis	biological_process
GO:0002675	positive regulation of acute inflammatory response	biological_process
GO:0002690	positive regulation of leukocyte chemotaxis	biological_process
GO:0006469	negative regulation of protein kinase activity	biological_process
GO:0006953	acute-phase response	biological_process
GO:0006954	inflammatory response	biological_process
GO:0006955	immune response	biological_process
GO:0006959	humoral immune response	biological_process
GO:0007568	aging	biological_process
GO:0008284	positive regulation of cell proliferation	biological_process
GO:0008285	negative regulation of cell proliferation	biological_process
GO:0008360	regulation of cell shape	biological_process
GO:0009408	response to heat	biological_process
GO:0009409	response to cold	biological_process
GO:0009611	response to wounding	biological_process
GO:0009612	response to mechanical stimulus	biological_process
GO:0009617	response to bacterium	biological_process
GO:0010574	regulation of vascular endothelial growth factor production	biological_process
GO:0010888	negative regulation of lipid storage	biological_process
GO:0014070	response to organic cyclic compound	biological_process
GO:0016049	cell growth	biological_process
GO:0019221	cytokine-mediated signaling pathway	biological_process
GO:0030168	platelet activation	biological_process
GO:0031000	response to caffeine	biological_process
GO:0031018	endocrine pancreas development	biological_process
GO:0031175	neuron projection development	biological_process
GO:0031667	response to nutrient levels	biological_process
GO:0032494	response to peptidoglycan	biological_process
GO:0032496	response to lipopolysaccharide	biological_process
GO:0032722	positive regulation of chemokine production	biological_process
GO:0032755	positive regulation of interleukin-6 production	biological_process
GO:0032868	response to insulin stimulus	biological_process
GO:0032966	negative regulation of collagen biosynthetic process	biological_process
GO:0033138	positive regulation of peptidyl-serine phosphorylation	biological_process
GO:0033160	positive regulation of protein import into nucleus, translocation	biological_process
GO:0034097	response to cytokine stimulus	biological_process
GO:0042102	positive regulation of T cell proliferation	biological_process
GO:0042110	T cell activation	biological_process
GO:0042493	response to drug	biological_process
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	biological_process
GO:0042832	defense response to protozoan	biological_process
GO:0042981	regulation of apoptotic process	biological_process
GO:0043066	negative regulation of apoptotic process	biological_process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	biological_process
GO:0043200	response to amino acid stimulus	biological_process
GO:0043410	positive regulation of MAPKKK cascade	biological_process
GO:0043526	neuroprotection	biological_process
GO:0045079	negative regulation of chemokine biosynthetic process	biological_process
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	biological_process
GO:0045429	positive regulation of nitric oxide biosynthetic process	biological_process
GO:0045454	cell redox homeostasis	biological_process
GO:0045599	negative regulation of fat cell differentiation	biological_process
GO:0045630	positive regulation of T-helper 2 cell differentiation	biological_process
GO:0045666	positive regulation of neuron differentiation	biological_process
GO:0045669	positive regulation of osteoblast differentiation	biological_process
GO:0045721	negative regulation of gluconeogenesis	biological_process
GO:0045727	positive regulation of translation	biological_process
GO:0045740	positive regulation of DNA replication	biological_process
GO:0045765	regulation of angiogenesis	biological_process
GO:0045768	positive regulation of anti-apoptosis	biological_process
GO:0045893	positive regulation of transcription, DNA-dependent	biological_process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological_process
GO:0046427	positive regulation of JAK-STAT cascade	biological_process
GO:0046677	response to antibiotic	biological_process
GO:0046716	muscle cell homeostasis	biological_process
GO:0046849	bone remodeling	biological_process
GO:0046888	negative regulation of hormone secretion	biological_process
GO:0048635	negative regulation of muscle organ development	biological_process
GO:0048661	positive regulation of smooth muscle cell proliferation	biological_process
GO:0050679	positive regulation of epithelial cell proliferation	biological_process
GO:0050710	negative regulation of cytokine secretion	biological_process
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	biological_process
GO:0050829	defense response to Gram-negative bacterium	biological_process
GO:0050830	defense response to Gram-positive bacterium	biological_process
GO:0050871	positive regulation of B cell activation	biological_process
GO:0051024	positive regulation of immunoglobulin secretion	biological_process
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	biological_process
GO:0051092	positive regulation of NF-kappaB transcription factor activity	biological_process
GO:0051384	response to glucocorticoid stimulus	biological_process
GO:0051592	response to calcium ion	biological_process
GO:0051602	response to electrical stimulus	biological_process
GO:0051607	defense response to virus	biological_process
GO:0051897	positive regulation of protein kinase B signaling cascade	biological_process
GO:0051971	positive regulation of transmission of nerve impulse	biological_process
GO:0060445	branching involved in salivary gland morphogenesis	biological_process
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	biological_process
GO:0070091	glucagon secretion	biological_process
GO:0070102	interleukin-6-mediated signaling pathway	biological_process
GO:0070301	cellular response to hydrogen peroxide	biological_process
GO:0070374	positive regulation of ERK1 and ERK2 cascade	biological_process
GO:2000366	positive regulation of STAT protein import into nucleus	biological_process
GO:0005576	extracellular region	cellular_component
GO:0005615	extracellular space	cellular_component
GO:0005896	interleukin-6 receptor complex	cellular_component
GO:0009897	external side of plasma membrane	cellular_component
GO:0005125	cytokine activity	molecular_function
GO:0005138	interleukin-6 receptor binding	molecular_function
GO:0008083	growth factor activity	molecular_function
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