insulin-like growth factor 1 (somatomedin C)


IGF1 (may also be known as: IGF1A)




igf1 Danio rerio
Igf1 Mus musculus
Igf1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1181 Morning IGF1 decline Physiological plasma Human IGF1 51.0% Decrease Hormone Level

GO Terms

GO IDGO TermGO Category
GO:0001501 skeletal system development biological_process
GO:0001932 regulation of protein phosphorylation biological_process
GO:0001974 blood vessel remodeling biological_process
GO:0002576 platelet degranulation biological_process
GO:0006260 DNA replication biological_process
GO:0006916 anti-apoptosis biological_process
GO:0006928 cellular component movement biological_process
GO:0007165 signal transduction biological_process
GO:0007265 Ras protein signal transduction biological_process
GO:0007399 nervous system development biological_process
GO:0007517 muscle organ development biological_process
GO:0007596 blood coagulation biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0008285 negative regulation of cell proliferation biological_process
GO:0009441 glycolate metabolic process biological_process
GO:0010001 glial cell differentiation biological_process
GO:0010613 positive regulation of cardiac muscle hypertrophy biological_process
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade biological_process
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration biological_process
GO:0014896 muscle hypertrophy biological_process
GO:0014904 myotube cell development biological_process
GO:0014911 positive regulation of smooth muscle cell migration biological_process
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation biological_process
GO:0030104 water homeostasis biological_process
GO:0030166 proteoglycan biosynthetic process biological_process
GO:0030168 platelet activation biological_process
GO:0030879 mammary gland development biological_process
GO:0031017 exocrine pancreas development biological_process
GO:0032878 regulation of establishment or maintenance of cell polarity biological_process
GO:0033160 positive regulation of protein import into nucleus, translocation biological_process
GO:0034392 negative regulation of smooth muscle cell apoptosis biological_process
GO:0035630 bone mineralization involved in bone maturation biological_process
GO:0040014 regulation of multicellular organism growth biological_process
GO:0042104 positive regulation of activated T cell proliferation biological_process
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein biological_process
GO:0043388 positive regulation of DNA binding biological_process
GO:0043410 positive regulation of MAPKKK cascade biological_process
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway biological_process
GO:0045445 myoblast differentiation biological_process
GO:0045669 positive regulation of osteoblast differentiation biological_process
GO:0045725 positive regulation of glycogen biosynthetic process biological_process
GO:0045740 positive regulation of DNA replication biological_process
GO:0045821 positive regulation of glycolysis biological_process
GO:0045840 positive regulation of mitosis biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0046326 positive regulation of glucose import biological_process
GO:0046579 positive regulation of Ras protein signal transduction biological_process
GO:0048015 phosphatidylinositol-mediated signaling biological_process
GO:0048146 positive regulation of fibroblast proliferation biological_process
GO:0048286 lung alveolus development biological_process
GO:0048661 positive regulation of smooth muscle cell proliferation biological_process
GO:0048754 branching morphogenesis of a tube biological_process
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process biological_process
GO:0050679 positive regulation of epithelial cell proliferation biological_process
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation biological_process
GO:0051246 regulation of protein metabolic process biological_process
GO:0051450 myoblast proliferation biological_process
GO:0051897 positive regulation of protein kinase B signaling cascade biological_process
GO:0060426 lung vasculature development biological_process
GO:0060463 lung lobe morphogenesis biological_process
GO:0060509 Type I pneumocyte differentiation biological_process
GO:0060510 Type II pneumocyte differentiation biological_process
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis biological_process
GO:0060736 prostate gland growth biological_process
GO:0060740 prostate gland epithelium morphogenesis biological_process
GO:0060741 prostate gland stromal morphogenesis biological_process
GO:0060766 negative regulation of androgen receptor signaling pathway biological_process
GO:0070373 negative regulation of ERK1 and ERK2 cascade biological_process
GO:0070886 positive regulation of calcineurin-NFAT signaling pathway biological_process
GO:0090201 negative regulation of release of cytochrome c from mitochondria biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0016942 insulin-like growth factor binding protein complex cellular_component
GO:0031093 platelet alpha granule lumen cellular_component
GO:0005158 insulin receptor binding molecular_function
GO:0005159 insulin-like growth factor receptor binding molecular_function
GO:0005178 integrin binding molecular_function
GO:0005179 hormone activity molecular_function
GO:0005515 protein binding molecular_function
GO:0008083 growth factor activity molecular_function