5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
Symbol
HTR7
(may also be known as: None)
Organism
Human
Description
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| LOC562111 | Danio rerio | |
| Htr7 | Mus musculus | |
| Htr7 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0007187 | G-protein signaling, coupled to cyclic nucleotide second messenger | biological_process | |
| GO:0007192 | activation of adenylate cyclase activity by serotonin receptor signaling pathway | biological_process | |
| GO:0007210 | serotonin receptor signaling pathway | biological_process | |
| GO:0007268 | synaptic transmission | biological_process | |
| GO:0007623 | circadian rhythm | biological_process | |
| GO:0008015 | blood circulation | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0005887 | integral to plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0004871 | signal transducer activity | molecular_function | |
| GO:0004872 | receptor activity | molecular_function | |
| GO:0004930 | G-protein coupled receptor activity | molecular_function | |
| GO:0004993 | serotonin receptor activity | molecular_function | |
| GO:0030594 | neurotransmitter receptor activity | molecular_function | |