ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Symbol
ST6GALNAC6
(may also be known as: None)
Organism
Human
Description
ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).[supplied by OMIM, Mar 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| st6galnac6 | Danio rerio | |
| St6galnac6 | Mus musculus | |
| Siat7F | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA3824 | Gene expression of ST6GALNAC6 decreases with age | Molecular | skin | Human | ST6GALNAC6 | — |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0001574 | ganglioside biosynthetic process | biological_process | |
| GO:0006486 | protein glycosylation | biological_process | |
| GO:0006677 | glycosylceramide metabolic process | biological_process | |
| GO:0006687 | glycosphingolipid metabolic process | biological_process | |
| GO:0009100 | glycoprotein metabolic process | biological_process | |
| GO:0009312 | oligosaccharide biosynthetic process | biological_process | |
| GO:0009988 | cell-cell recognition | biological_process | |
| GO:0000139 | Golgi membrane | cellular_component | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005794 | Golgi apparatus | cellular_component | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0030173 | integral to Golgi membrane | cellular_component | |
| GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity | molecular_function | |
| GO:0008373 | sialyltransferase activity | molecular_function | |