hyaluronan synthase 3

Symbol

HAS3 (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Orthologs

SymbolSpecies
has3 Danio rerio
Has3 Mus musculus
Has3 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2069 hyaluronan synthase 3 increases with age Molecular ovary Human HAS3 60.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0005975 carbohydrate metabolic process biological_process
GO:0030213 hyaluronan biosynthetic process biological_process
GO:0005887 integral to plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0016757 transferase activity, transferring glycosyl groups molecular_function
GO:0050501 hyaluronan synthase activity molecular_function