pyrroline-5-carboxylate reductase family, member 2
Symbol
PYCR2
(may also be known as: None)
Organism
Human
Description
This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
Orthologs
| Symbol | Species | |
|---|---|---|
| CELE_M153.1 | Caenorhabditis elegans | |
| CG5840 | Drosophila melanogaster | |
| zgc:110655 | Danio rerio | |
| Pycr2 | Mus musculus | |
| Pycr2 | Rattus norvegicus | |
| PRO3 | Saccharomyces cerevisiae | |
| pro3 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006561 | proline biosynthetic process | biological_process | |
| GO:0008652 | cellular amino acid biosynthetic process | biological_process | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0004735 | pyrroline-5-carboxylate reductase activity | molecular_function | |
| GO:0016491 | oxidoreductase activity | molecular_function | |
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | molecular_function | |